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CAT-080 - CA Spectrum Infrastructure Manager r9(R) Administrator - Dump Information

Vendor : CA-Technologies
Exam Code : CAT-080
Exam Name : CA Spectrum Infrastructure Manager r9(R) Administrator
Questions and Answers : 40 Q & A
Updated On : January 9, 2018
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CAT-080 Questions and Answers

QUESTION: 36

Before shutting down SpectroSERVER for an emergency maintenance, you want to send a message to all OneClick users who currently log in to the CA Spectrum OneClick Console. Where do you find the currently logged in users?

  1. Tomcat log file
  2. Users tab in the OneClick Console
  3. Client Details tab in the OneClick Console
  4. Users tab in the CA Spectrum Control Panel

Answer: C


QUESTION: 37

A reusable set of user privileges that you can assign to a security community is known as:

  1. A Role.
  2. A Universe.
  3. A Neighbor.
  4. A Global Privilege.

Answer: A


QUESTION: 38

In CA Spectrum, three customizable scripts are provided to display alarm notifications. Which of these scripts is invoked when an alarm is generated?

  1. SetScript
  2. ClearScript
  3. UpdateScript
  4. ExecuteScript

Answer: A


QUESTION: 39

Which attribute makes a model significant or insignificant?

  1. Significance
  2. Security String
  3. Value when Red
  4. Value when Down

Answer: C


QUESTION: 40

CA Spectrum server, client, and utility applications are started and stopped by:

  1. ArchMgr
  2. Processd
  3. SSdbbad
  4. Performance View client

Answer: B


CA-Technologies CAT-080 Exam (CA Spectrum Infrastructure Manager r9(R) Administrator) Detailed Information

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Where can I take a certification exam?
You can register to take an online proctored certification exam from your home or office, or schedule your exam at a Kryterion testing center location near you. Kryterion has testing centers in over 750 locations across the globe.
What is the format of a certification exam?
The certification exam is timed and comprises multiple choice questions. It is a proctored exam offered at a third party facility. Typically you will be presented with four answer choices, and you will select one correct answer. In the event there are two or more correct answers, you will be prompted to select the number of correct answers.
For how long is the certification valid, and what is the recertification policy?
Certification credentials are based on the major product release (such as r14), and the credential is issued as r14.x to account for subsequent minor point releases. There is no annual requirement to recertify for the same major release of a product (r14) or a minor point release (r14.1). An updated certification exam will be available for each major product release (r15, r16, and so forth). CA Employees and Partners are expected to get recertified for each major product release for which they require a credential.
Periodic updates to the exams ensure compatibility with minor point releases (such as r14.1).
On rare occasions CA Technologies may deem a minor point-release (such as r14.5) significant enough to warrant certification, in which case a new certification exam will be made available with the credential that bears that specific point release (for example, r14.5).
Which products have certifications?
Check the CA Technologies Certification page for a current table of products and related credentials. Click on the credential of interest to access resources that will help you prepare for the exam.
What is the duration of the exam?
The exams are generally 90 minutes in length.
How do I create an account and register for an exam?
Create your user account at webassessor.com/catechnologies. You may use your account to take any number of certification exams.
How can I receive help and support with account creation and registration on the Webassessor.com/CATechnologies site?
Contact the Kryterion Testing Network Support team at 800-403-6199 (US and Canada) or +1 602-281-3591 Monday 7:00 a.m. through Saturday 7:00 a.m. (Pacific Time) or send an email to ktnsupport@kryteriononline.com.
How can I receive help and support with Online Proctored (OLP) Services? (Installing software; Biometric enrollment; Test launch process)
Login at webassessor.com/catechnologies and follow the instructions to prepare for your online proctored exam. You will need to install the Sentinel software and create your biometric profile, after which you can register for your exam and schedule a date and time. You must create your biometric profile at least 24 hours prior to your online proctored exam. Refer to the guide below to review the technical requirements for your external webcam, microphone, and computer:
Preparing for Your Exam
If you have system or setup related questions the instructions are not able to answer, contact the Kryterion Online Proctored (OLP) Services Support team at olpsupport@kryteriononline.com.
How can I receive help and support finding a testing center or finding available dates and times to travel to a testing center?
Contact the Kryterion Testing Network Support team at 800-403-6199 (US and Canada) or +1 602-281-3591 Monday through Friday from 7:00 a.m. to 4:00 p.m. (Pacific Time) or send an email to ktnsupport@kryteriononline.com.
Is there a cost associated with a Certification exam?
Yes, the price for a Certification exam is USD 150-200 depending on your country, and pricing is posted at webassessor.com/catechnologies in the online registration page.
How do I pay for an exam?
The exam fees are collected and administered directly through the KryterionOnline Webassessor website.
What is the cancellation policy and can I reschedule my exam?
If you registered to take your exam at a Kryterion testing center, you can cancel or reschedule your exam up to 72 hours before your scheduled exam time. To reschedule, log into your account at webassessor.com/catechnologies, click on the details of your registered exam, and select 'Reschedule'.
If you registered to take an online proctored (OLP) exam, you can reschedule your exam up to 24 hours before your scheduled exam time. To reschedule, log into your account at webassessor.com/catechnologies, click on the details of your registered exam, and select 'Reschedule'.
You will not be refunded any portion of the exam fee, or any portion of the value of a coupon or voucher, if you do not reschedule in time or if you miss your exam appointment. Exceptions will be made for bereavement or illness supported by appropriate medical documentation.
What happens if I miss my exam appointment?
If you miss your exam appointment, you will be charged the full amount and will not be eligible for reimbursement. Terms and details will be provided to you at the time you schedule your exam. Note for CA Technologies employees: If you use a voucher to register for an exam and fail to cancel or reschedule, CA Technologies is still charged a fee, and these charges are reported to CA Technologies management.
Do customers or partners receive discounts on exams?
No, there are no standing discounts available to customers and partners for the CA Technologies certification exams. The CA Partner Program may leverage the Cost Relief program during certain periods in order to distribute vouchers for nominal discounts. However, the exams are priced reasonably. Check webassessor.com/catechnologies for pricing by country.
Will customers or partners be reimbursed for exams?
No, there are no reimbursements available for the CA Technologies certification exams.
Can partners leverage the Cost Relief program for Certification?
Yes, the Cost Relief program applies to both training and certification. The Channel Account Manager must make a request online using the Partner Education Training approval form.
Do college students receive discounts on exams?
Yes. If you are a full-time college student in good academic standing, please contact us at certification@ca.com and attach a JPEG image of your current student identification card. We will email you a coupon which will enable you to receive up to a 60% discount. You are limited to two coupons per 12-month period.
Are there any resources available to help me prepare for an exam?
Recommended Learning Paths and other resources are available to help you prepare for the certification exams.
Please visit the CA Technologies Certification page to download the Exam Study Guide that outlines the recommended training for each product certification and the topic areas tested.
Where can I register for product training?
Customers: You can register for product training through the CA Education Portal. To quickly access the recommended product training in the CA Education Portal, click on each course in the Learning Path.
Partners: You can register for product training through the Partner Catalog of the CA Education Portal. To access the Partner Catalog, log into Communities at CA using your partner credentials, go to CA Education, and choose “Find a Course.” It is important to note that unless you are logged into Communities at CA with your partner credentials, you will not be able to view the Partner Catalog. For questions, contact CA Customer Care.
What if I would like to take a course to prepare for certification, but the course is not available in the current course calendar?
You can study the information at your own pace. Alternatively, you can put yourself on the course request list, and with enough interest, a course will be made publically available. Go to the Course Catalog, find the course on the CA Education Portal, and click on Request Information to make your request.
Can I take an exam without taking preparatory courses?
Yes, if you feel you possess the required knowledge, you may register and take an exam. However, CA Technologies recommends that you take the associated courses, perform all labs, and gain hands-on experience prior to attempting an exam. Be sure and review the Exam Study Guide that shows the topic areas being tested.
When will I find out if I passed my exam?
After you have completed your exam, you will immediately receive a message by email with your score and a topic-level report.
What if I do not pass the exam on my first attempt? Can I retake the exam?
You may register for your first retake immediately. For subsequent retakes you are required to wait at least thirty (30) calendar days from the date of your last attempt.
Is there a limit to the number of times I can take an exam?
You are allowed two retakes for an exam, for a total of three attempts. Be aware that there is a waiting period between exams after the first two attempts.
If I did not pass an exam on my first attempt, will I receive a discount on future attempts?
The published fee associated with the first exam will be required for all future attempts. There are no discounts offered for multiple attempts.
Will I receive a Certification distinction?
Yes, upon successful exam and certification activity completion, you will receive an email from CA Technologies within five business days that contains the Certification from CA Technologies diploma and logo usage guidelines.
How can a third party verify my certification status?
Your email report and CA certification diploma can be used to verify your certification status. If a third party requires verification, they may contact certification@ca.com.
Do the exams change, and do the topics covered by an exam change?
CA Technologies may modify an exam, test objective/topic, and the requirements for obtaining or maintaining certification at any time in its sole discretion. It is your responsibility to keep informed of such modifications. The posted Exam Study Guides identify exam objectives and serve as a basis for exam preparation.
What is the exam security policy at CA Technologies?
Only qualified candidates who demonstrate competency by successfully passing the CA Technologies certification exam will be awarded certification credentials. Prospective certification candidates are encouraged to prepare for the exam using the Exam Study Guide and other materials available on the CA Certification page.
To safeguard the integrity of the certification program, CA Technologies requires all candidates to behave in an ethical manner and to comply with the rules of the third-party test center for on-site proctoring and on-line proctoring. The validity of the certification program depends on the exam content remaining secure and undisclosed to other potential certification candidates. CA Technologies will not tolerate cheating, fraud, or misconduct, which includes but is not limited to the following:
Obtaining, whether through purchase or otherwise acquiring, unauthorized exam preparation materials from any non-CA website
Obtaining, whether through purchase or otherwise acquiring, unauthorized exam questions from any non-CA website, including brain dump websites
Acquiring or attempting to acquire exam questions through online communities, chat rooms, forums, and social networking sites
Acquiring or attempting to acquire exam content through CA Subject Matter Experts, CA Support Staff, or CA Certified Professionals
Using or attempting to use a proxy to sit for the exam in your place
Taking or attempting to take an exam for someone else
Receiving or giving assistance during an exam
Sharing exam questions or answers with a potential certification candidate
Violating testing center rules
Falsifying a diploma or score report
Using a CA Technologies certification logo or credential to which you are not entitled
CA Technologies reserves the right to take any actions it deems reasonably appropriate in the case of suspected misconduct or violation of the terms of the Non-Disclosure Agreement, including, but not limited to, cancelling an exam result, revoking exam or certification status, terminating use of the Designation, requiring a candidate to retake an exam, banning a candidate from the certification program, and reporting misconduct to the candidate’s employer. CA Technologies considers cheating a serious offense that warrants disciplinary action, up to and including termination of employment.
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Accreditation is recognition and validation for those who have demonstrated superior levels of business, sales and technical expertise that address customer solution needs in areas of operation, administration, design, implementation and troubleshooting.
Accreditation involves successfully completing a timed exam in an open-book environment. The exam may be taken at a CA learning center or from the comfort of your living room or office.
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Customers can search the Customer Catalog, entering the product name followed by “exam.” You can also search by course code. Then select the Add to Cart button to register.
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What is CA Accreditation?
Accreditation is recognition and validation which distinguishes individuals who have demonstrated superior levels of business, sales and technical expertise that address customer Enterprise solution needs in areas of operation, administration, design, implementation and troubleshooting.
CA Accreditation involves successfully completing a timed exam in an open-book environment. The exam may be taken at a CA learning center or in your living room or office. CA Accreditation testing allows you to use your real-world problem-solving experiences to solve real-world IT problems.
Do I have to pay for Accreditation exams?
There is no cost to take an Accreditation exam at this time.
How do I become CA Accredited?
You must successfully complete the Accreditation exam with a passing score. You may take the exam at a CA learning center or online in your home or office.
How do I prepare for my exam?
The CA Accreditation exam assesses your knowledge of a CA product. Students who complete the associated CA Education courses achieve higher scores on CA Accreditation Exams.
What do I need to have ready when I take the exam?
You can take an Accreditation exam at a CA Training Center, in your home, or at your office. For your convenience, all Accreditation exams are available through the CA Education Portal. Exams are delivered online and are open book. You should test your Internet connection ahead of time, and you may refer to course materials during the exam.
What is the format of an Accreditation exam?
CA Accreditation exams are timed exams consisting of multiple choice questions.
What does a typical exam question look like?
Example Question: Which protocols does Single Logout support?
1. SAML 1.0
2. SAML 2.0
3. SAML 1.1
4. Liberty V1.x
5. Web Services Federation (WS-Federation)
A. 1, 2, and 3
B. 2, 3, and 4
C. 2, 4, and 5
D. 3, 4, and 5
Example Question: Which component of CA Single Sign-On installs SAML authentication schemes?
A. Affiliate Agent
B. Application Agent
C. Web Agent Option Pack
D. Policy Server Option Pack
Example Question: What is the MOST appropriate step to perform when initialization fails following installation of eTrust Federation components?
A. Check the configuration environment.
B. Uninstall and reconfigure all components.
C. Compare all library files installed to identify the failure reason.
D. Ensure installed products are version compatible with one another.
How do I register for an exam?
Customer, partner and employee exams are hosted online in the CA Education Portal. To take an Accreditation exam, follow these steps:
Customer and Partner Registration
Go to the CA Education Course Catalog:
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Partner Catalog Login
In the Keywords field, enter the product name followed by “exam.” You can also search for your exam by entering the course code.
To register for an exam, click the Add to Cart button. At that point, you will be prompted to log in, or register for the first time, before you can continue.
After you complete your registration and enrollment, review your selections and click the Finish button. You can then view your selection in the Training to Do List under the My Learning tab.
When you are ready to take the exam, select Go to Content to launch the exam. Please do not select Go to Content until you are ready to complete the exam; otherwise, it counts as an attempt.
Additional Information for Partners
Partners are eligible* to receive:
Free web-based training (including all 100-400 level sales, technical and support courses)
Discounted instructor-led training
For assistance accessing these benefits, please contact CA Customer Care.
*Partner must be an active CA partner.
Please note that if you do not see the course or exam that you are looking for, it is necessary to first log in to the CA Education Portal, and a complete list will be available.
Employee Registration
Go to the CA Employee Education Portal Course Search page.
In the Keywords field, enter the product name followed by “exam.” You can also search for your exam by entering the course code.
When you are ready to take the exam, select Go to Content to launch the exam. Please do not select Go to Content until you are ready to complete the exam; otherwise, it counts as an attempt.
Difficulty accessing the exam?
We recommend that you use a reliable connection to sit for the exam. If you lose network connectivity while writing the exam or if you prematurely exit the exam and can no longer access it, take the appropriate corrective action:
For Customers and Partners:
Please contact CA Customer Care. Note the exam code, and let the Support personnel know that you require an exam reset due to network connectivity causing a lock-out.
For CA Employees:
Open a Service Desk issue to request Exam User Reset:
Select Create a New Request.
If prompted to search knowledge base, select Cancel.
In the Applications section, look under E for Education Portal, and then Education Portal Support.
Be sure and provide the exam code.
What is the exam passing score? Does it change?
CA makes best efforts to maintain passing scores of 80%. The difficulty level of each Accreditation exam is adjusted by a team of internal and third-party experts to allow specific passing and fail rate thresholds. Exceptions to the 80% score occur during Beta testing of new exams, when the passing score may be lowered temporarily (for Beta test takers and early-adopter test takers) while the optimal difficulty level is being established. All of these efforts are aimed at establishing and maintaining the fairness, validity and reliability of CA exams.
Can I retake the exam if I fail?
If you fail an exam you may take the exam again immediately or at your convenience. You have two attempts at exams. If you are not successful, then you should take available training.
How do I print my Accreditation certificate?
After you have passed the exam, you may print your CA Accreditation certificate. In the CA Education Portal, go to My Learning, then Training Completed.
CA Education Portal Login:
Customers and Partners
Employees
For learning path completion diplomas, please contact accreditations@ca.com indicating the specific role-based path, and we will email the diploma to you in about three business days. If you do not receive your diploma within two weeks of successful learning path completion, please email us and we will be glad to email you a new one. Be sure and add accreditations@ca.com to your allowed sender list.
How do I obtain a copy of my score report?
Log in to your student account in the CA Education Portal, select My Learning, then Training Completed to see a list of your completed exams and scores.
CA Education Portal Login:
Customers and Partners
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  • "Argument CompositeOperation is invalid" error Performing Composite Operations on Oracle Database is very comparable to SQL Server Database. I just want to element out one mistake developers might conveniently make during the ship port configuration. For any composite operation, the generated binding script would not consist of the composition operation tag in soap motion header, therefore a brand new line has to be manually added for every composite operation all over the send port configuration.
    For WCF SQL Adapter, it appears like <Operation name="CompositeOperationName" motion="CompositeOperation" />
    but if you do the identical aspect if you configure WCF Oracle adapter, you'll receive "Argument CompositeOperation is invalid" error in adventure log at runtime.
    The correct layout for Oracle adapter should still look like
     <Operation identify="CompositeOperationName" motion="http://Microsoft.LobServices.OracleDB/2007/03/CompositeOperation" />     The change is for Oracle you should add namespace earlier than "CompositeOperation". It makes feel bacause here is a Microsoft product and SQL Server Adapter is the default adapter, so handiest SQL Server Adapter does not require namespace.
    For an entire reference on the way to performing composite operations on Oracle database may well be found here on MSDN.
    ...Edmund Zhao

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  • Trafficking Dynamics of PCSK9-brought about LDLR Degradation: center of attention on Human PCSK9 Mutations and C-Terminal domain summary PCSK9 is a secreted ligand and poor publish-translational regulator of low-density lipoprotein receptor (LDLR) in hepatocytes. gain-of-feature (GOF) or loss-of-function (LOF) mutations in PCSK9 are at once correlated with excessive or low plasma LDL-cholesterol levels, respectively. for this reason, PCSK9 is a prevailing lipid-lowering target to keep away from coronary heart ailments and stroke. Herein, we fused monomeric fluorescent proteins to PCSK9 and LDLR to visualize their intra- and extracellular trafficking dynamics via reside confocal microscopy. Fluorescence recuperation after photobleaching (FRAP) showed that PCSK9 LOF R46L mutant and GOF mutations S127R and D129G, but now not the LDLR excessive-affinity mutant D374Y, enormously accelerate PCSK9 exit from the endoplasmic reticulum (ER). Quantitative evaluation of inverse FRAP printed that handiest R46L presented a a whole lot slower trafficking from the trans-Golgi network (TGN) to the plasma membrane and a lower cell fraction likely suggesting accumulation or delayed exit at the TGN as an underlying mechanism. whereas now not primarily concerned in LDLR binding, PCSK9 C-terminal area (CTD) changed into discovered to be standard to induce LDLR degradation each upon its overexpression in cells or by the use of the extracellular pathway. Our information printed that PCSK9 CTD is required for the localization of PCSK9 at the TGN and increases its LDLR-mediated endocytosis. curiously, intracellular lysosomal concentrated on of PCSK9-ΔCTD became capable of rescue its potential to result in LDLR degradation emphasizing a task of the CTD within the sorting of PCSK9-LDLR complex against late endocytic cubicles. eventually, we validated our dual fluorescence equipment as a telephone based mostly-assay by way of combating PCSK9 internalization using a PCSK9-LDLR blockading antibody, which may well be expended to establish protein, peptide or small molecule inhibitors of PCSK9.
    quotation: Poirier S, Hamouda HA, Villeneuve L, Demers A, Mayer G (2016) Trafficking Dynamics of PCSK9-induced LDLR Degradation: focal point on Human PCSK9 Mutations and C-Terminal area. PLoS ONE eleven(6): e0157230. doi:10.1371/journal.pone.0157230
    Editor: Makoto Kanzaki, Tohoku tuition, JAPAN
    got: January 14, 2016; accepted: may additionally 26, 2016; published: June 9, 2016
    Copyright: © 2016 Poirier et al. here's an open entry article allotted beneath the terms of the inventive Commons Attribution License, which makes it possible for unrestricted use, distribution, and copy in any medium, offered the common author and supply are credited.
    statistics Availability: All significant information are inside the paper and its assisting suggestions files.
    Funding: This work became supported with the aid of research provides from the Canadian Institutes of fitness analysis (CIHR - Institute of foodstuff, Metabolism and Diabetes; MOP133598), the heart and Stroke basis of Canada, the Fonds de Recherche du Québec - Santé and the Montreal coronary heart Institute foundation to G.M.
    Competing pursuits: The authors have declared that no competing pursuits exist.
    Introduction Subendothelial retention of low-density lipoproteins (LDL) within the arteries is a key initiating experience in atherogenesis often resulting in coronary heart illnesses (CHD) or stroke [1]. Familial hypercholesterolemia (FH) is a typical genetic disease linked ordinarily with mutations at LDLR, APOB and PCSK9 loci, clinically characterised by excessive degrees of circulating LDL particles and premature CHD [2]. Proprotein convertase subtilisin-kexin classification 9 (PCSK9; [3]) turned into proven to be a natural inducer of LDLR degradation [4], thereby rising LDL particle tiers in the bloodstream. while PCSK9 profit-of-function (GOF) mutations may end up in high plasma ranges of LDL [5], PCSK9 loss-of-feature (LOF) mutations result in life-lengthy discount of circulating LDL and might greatly in the reduction of primary CHD routine in humans [6, 7]. for this reason, it is awaited that pharmacological inhibition of PCSK9 will additionally outcome in insurance policy towards CHD [7].
    within the adulthood, PCSK9 is highly expressed in liver and to a lesser extent in different cholesterogenic tissues such because the intestine and kidneys [3] and is positively regulated by way of statins (HMG-CoA reductase inhibitors; [8]) via sterol regulatory point-binding protein (SREBP)-2 [9] cooperatively with hepatocyte nuclear factor (HNF)-1 alpha [10]. PCSK9 encodes for a secreted 692-amino acid (aa) glycoprotein structurally composed of a sign peptide (aa 1–30), prosegment (seasoned; aa 31–152), catalytic (Cat; aa 153–454) and C-terminal cysteine-histidine-rich (CTD; aa 455–692) domains [11]. inside the endoplasmic reticulum (ER), the zymogen proPCSK9 is synthesized as a ~74 kDa protein that undergoes autocatalytic intramolecular cleavage at position 152 to form a ~14 kDa inhibitory prosegment that remains noncovalently bonded to the ~60 kDa mature PCSK9 [3, 12, 13]. This tightly sure heterodimeric complex forming an inactive enzyme is absolutely required for ER exit and secretion. a chic study CAT-080 printed that transport of PCSK9 from the ER to the Golgi apparatus requires the SEC24A subunit to be incorporated into coat protein complicated II (COPII)-covered vesicles [14]. moreover, our fresh work tested that, independently of its chaperone recreation, GRP94 binds PCSK9 within the ER and prevents premature LDLR degradation [15]. youngsters their in vivo roles on PCSK9 function are questionable [16], sortilin [17] and amyloid precursor-like protein 2 [18] had been recognized as sorting receptors helping PCSK9 secretion and trafficking towards late endocytic cubicles, respectively. A body of evidence shows that PCSK9 goals LDLR for degradation by way of two pathways: an intracellular one from the trans-Golgi community (TGN) without delay to late endosomes/lysosomes, involving clathrin mild chains [19], and an extracellular one [20, 21] requiring the cytosolic adaptor ARH (autosomal recessive hypercholesterolemia) and mediated by means of clathrin heavy chain endocytosis of cell floor PCSK9-LDLR complicated [22, 23]. besides the fact that children, the relative contributions of these molecular trafficking add-ons in every of the mobile pathways remain to be decided.
    Biochemical statistics showed that the surface of PCSK9 catalytic area, along side its N-terminus launched after prosegment cleavage, without delay interacts with the primary extracellular epidermal boom element-like repeat (EGF-A) of LDLR [24, 25], and that the affinity of this interplay tremendously raises at acidic pH [11, 26]. PCSK9-D374Y GOF mutant has a markedly increased affinity for LDLR through allowing a hydrogen bond to kind at impartial pH with H306 of the LDLR EGF-a site [25–27], leading to an exceedingly severe FH phenotype [28]. interestingly, removal of the N-terminal acid stretch (aa 31–fifty three) of PCSK9 prosegment also strongly raises its binding to LDLR [25, 29]. in addition, it become proven that PCSK9 residue L108 makes van der Waals interactions with the LDLR β-propeller area, which can be potentiated in L108R, S127R or D129G prosegment PCSK9 GOF mutations [30, 31]. patients harboring the PCSK9 prosegment R46L LOF mutation had ~50% reduction in incidence of coronary pursuits due to a lifelong discount in LDL-ldl cholesterol of simplest 15% [6]. It has been discovered that the R46L variant does not affect PCSK9 endocytosis however has a 2-fold weaker affinity for LDLR leading to a slight discount of its capability to induce LDLR degradation [26]. Loss- or profit-of-function mutations in PCSK9 prosegment (e.g. R46L, S127R, D129G) or CTD (e.g., R496W and H553R), which are not essentially involved in LDLR EGF-A binding, show that these domains additionally take part within the legislation of PCSK9-brought on LDLR degradation by way of a mechanism for which we possess little or no tips.
    Independently of its catalytic activity [32], PCSK9 binds to LDLR and prevents its cellphone floor recycling through rerouting the receptor to late endocytic booths for degradation (reviewed in [23]). thus far, two prevailing mechanisms had been proposed to clarify the PCSK9-brought on LDLR degradation both counting on the elementary position of the PCSK9 CTD within the manner [33]. at the start, as soon as in acidic booths, the affinity of PCSK9 catalytic area for LDLR EGF-A is drastically accelerated and could permit interaction of the CTD with the LDLR ligand-binding area [34], creating a conformational trade in LDLR that would result in its shedding with the aid of γ-secretase and its degradation in lysosomes [35]. Secondly, it has been proposed that a putative transmembrane protein would connect PCSK9 by means of its CTD to cytosolic adaptors with a purpose to target the PCSK9-LDLR advanced to lysosomes [36]. youngsters the accurate position of PCSK9 CTD requires greater investigations, it has been proven that Annexin A2 [37, 38] or a monoclonal antibody [39] that in particular bind to the CTD each inhibited the PCSK9-brought about LDLR degradation.
    within the latest analyze, we developed a dual fluorescence cell-based assay and analyzed the trafficking dynamics of PCSK9 and LDLR both for intra- and extracellular pathways by means of live confocal microscopy. Our information revealed that PCSK9 CTD raises LDLR-mediated PCSK9 endocytosis and PCSK9 subcellular localization at the TGN. additionally, fusion of the transmembrane area and cytosolic tail of the lysosome-associated membrane protein-1 (Lamp1) to PCSK9 missing the CTD (PCSK9-ΔCTD) fully restored its means to set off LDLR degradation, suggesting a imperative role of the CTD as a trafficking determinant for the PCSK9-LDLR advanced. Comparative fluorescence healing after photobleaching (FRAP) analyses showed that the LOF R46L mutation in PCSK9 is linked to greater retention on the TGN. the usage of a PCSK9-LDLR blockading monoclonal antibody, we validated our cell-based mostly assay that can be used to reveal for purposeful knockdown libraries, biologics or small molecule inhibitors.
    substances and strategies Reagents and plasmids Human neutralizing recombinant anti-PCSK9 antibody (IgG1) turned into received from BPS Bioscience (Cat. #71207, lot #121204-D). TO-pro-three iodide become received from existence technologies (Cat. #T3605). Recombinant human PCSK9 (rhPCSK9; aa 31–692) and cDNAs encoding for full-size wild-class (WT) human PCSK9 and its GOF mutants D374Y and F379A, with a C-terminal V5 tag, cloned into pIRES2-EGFP were produced as described previously [40]. Subcloned pIRES2-EGFP plasmids encoding V5-tagged PCSK9 CTD (aa 1-31(Q31N)-405-692) and PCSK9-ΔCTD (aa 1–454), Timp1- and PCSK9-V5-TM-Ct-Lamp1 chimeras (WT, CTD or ΔCTD) and WT V5-tagged human LDLR have been generous presents from Dr. Nabil Seidah (Institut de Recherches Cliniques de Montréal). PCSK9-F379A-V5-TM-Ct-Lamp1 changed into generated by subcloning the F379A cassette from pIRES-PCSK9-F379A-V5 into pCMV3-hPCSK9-V5-TM-Ct-Lamp1 vector. other PCSK9 and LDLR mutants were generated by QuickChange II XL site-directed mutagenesis (Agilent, Cat. #200521) in the pIRES-hPCSK9-V5 and pIRES-hLDLR-V5 cDNA backbones, respectively. PCSK9-Δhinge-CTD (aa 1-31(Q31N)-440-692) was generated by two-step overlap PCR the use of the pIRES-hPCSK9-CTD-V5 as template with right here oligonucleotides: PCR1; 5’-GGGCGGTAGGCGTGTACGGTGG, 5’-GGCCACCAGTTTGGCAGAGAAGTGGATCAG and PCR2; 5’-CTCTGCCAAACTGGTGGCCGCCC, 5’-CGCACACCGGCCTTATTCCAAG and subcloned into the pIRES-V5 vector. The monomeric fluorescent Cherry coding cDNA changed into fused to PCSK9 C-terminus using pCMV-Cav1-mCherry as a template (Cat. #27705, Addgene) as described prior to now [40]. As indicated, all PCSK9 mutants had been subcloned from corresponding pIRES-hPCSK9-V5 into the pCMV-hPCSK9-mCherry spine cDNA. more advantageous eco-friendly fluorescence protein (EGFP) become fused to LDLR cDNA at its C-terminal (pCMV-hLDLR-EGFP) by means of PCR amplification and subcloned at AgeI/NotI into pIRES-hLDLR-V5 resulting in deletion of the V5-tag sequence and the internal ribosomal entry web site (IRES). All selected clones were verified by way of DNA sequencing.
    phone way of life and transfections Human hepatoma HepG2 cells had been routinely cultivated in Dulbecco’s modified Eagle’s medium (DMEM; Cat. #319-005-CL, Wisent) supplemented with 10% Fetal Bovine Serum (FBS; Cat. #080–350, Wisent). Human embryonic kidney 293 (HEK293) cells had been cultivated in complete DMEM devoid of sodium pyruvate (Cat. # 319-015-CL, Wisent). HepG2 had been transfected with Lipofectamine 3000 (Cat. #L3000008, existence technologies) or XtremeGENE 9 (Cat. #06365787001, Roche Diagnostics) according to the manufacturer’s strategies. HEK293 cells were transfected with linear polyethylenimine MW 25,000 (PEI; Cat. #23966, Polysciences) at ratio of 0.eight:0.2 PEI (μg):DNA (μg) per cm2 of cellphone floor area.
    Western blot analyses Cells had been washed thrice in phosphate-buffered saline (PBS) and lysed in 1x RIPA buffer (50 mM Tris/HCl, pH eight.0, 1% (v/v) Nonidet P40, 0.5% sodium deoxycholate, one hundred fifty mM NaCl and nil.1% (v/v) SDS) supplemented with 1x comprehensive Protease Inhibitor mixture (Cat. #eleven 697 498 001, Roche applied Science). Proteins from cell lysates and conditioned media were resolved by using eight% Tris-Glycine SDS-page and blotted on HyBond nitrocellulose membranes (Cat. #162–0115, Bio-Rad), blocked for 1 h in Tris-Buffered Saline-Tween 20 (TBS-T; 50mM Tris-HCl, pH 7.5, one hundred fifty mM NaCl, 0.1% Tween 20) containing 5% non-fats dry milk. Membranes have been then incubated in a single day in TBS-T supplemented with 1% non-fat milk and indicated antibodies: rabbit anti-PCSK9 [41] (1:2500), goat anti-human LDLR (1:one thousand; Cat. #AF2148, R&D techniques), mouse anti-V5-tag (1:5000; Cat. #A00641, GenScript), rabbit anti-β-actin (1:5000; Cat. #A2066, Sigma-Aldrich). acceptable HRP-conjugated secondary antibodies (1:10,000, GE healthcare) were used for detection the use of the Western Lightning ultra chemiluminescence equipment (Cat. #NEl112001EA, PerkinElmer) and BioFlex EC films (Cat. #CLEC810, InterScience).
    Immunocytochemistry and are living-cell imaging Cells plated on glass-bottom tradition dishes (Cat. #P35G-0-10-C, MatTek) have been washed 3 times with PBS and stuck with four% paraformaldehyde for 15 min. Following huge PBS washes, cells had been permeabilized or no longer, as indicated in determine legends, with 0.1% Triton X-one hundred/PBS for 10 min and incubated with a hundred and fifty mM glycine to stabilize the aldehydes. The cells have been then incubated for 30 min with 1% BSA (Fraction V; Cat. #BP1605, Sigma) containing or now not 0.1% Triton X-a hundred, adopted with the aid of overnight incubation at four°C with rabbit anti-human PCSK9 (1:250), mouse anti-V5 (1/500; Cat. #R960-025, existence applied sciences) and mouse anti-Golgin-ninety seven (1/500; Cat. #sc-59820, Santa Cruz Biotechnology). Specificity of endogenous PCSK9 labeling turned into performed via immunoadsorption with 1 μg/ml of recombinant human PCSK9 combined with the rabbit anti-human PCSK9 antibody (1:250) in 0.1% Triton X-one hundred/PBS and circled in a single day at four°C prior to incubation on cells. later on, cells were incubated for 60 min with corresponding Alexa Fluor-conjugated secondary antibodies (Molecular Probes) and mounted in ninety% glycerol containing 5% 1,four-diazabicyclo[2.2.2]octane (DABCO; Cat. #D27802, Sigma). For PCSK9-mCherry and LDLR-EGFP subcellular visualization, cells were transfected with corresponding plasmids or LDLR-EGFP expressing cells wereincubated with conditioned media containing PCSK9-mCherry. Twenty to forty-hours submit-remedies, cells were washed 3 times with PBS and fixed with four% paraformaldehyde/PBS for 15 min. For reside-mobile imaging, cells were transfected without or with PCSK9-mCherry and LDLR-EGFP or incubated with conditioned media containing PCSK9-mCherry in a CO2-, humidity- and temperature-managed chamber, from which images had been taken as indicated. Immunofluorescence or are living-mobilephone imaging analyses had been carried out with an Olympus FluoView FV10i or Zeiss LSM-710 confocal microscopes, respectively. The colocalization coefficient between PCSK9 or mutants thereof and Golgin-ninety seven changed into measured by estimating the Pearson's correlation coefficient (r) price using ImageJ colocalization plugin (NIH).
    FRAP and iFRAP Fluorescence recuperation after photobleaching (FRAP) and inverse FRAP (iFRAP) experiments were carried out with a Zei

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A These options have now been added to the CMA SmartDashboard in the IPS tab B The Merge and Override options are not supported in R71 C The options are available in Global Smart Dash boad / IPS tab in Profiles options D From the Provider-1 Properties in MDG, select the Global Policies tab and enable the check box 'Enable legacy SmartDefense merging options' Answer: B QUESTION: 171 You are the responsible administrator for two customers managed by your MSP You must configure each CMA with local objects as well as rules You have to configure the IPS accordingly In addition, you will configure and assign Global Rules for your customers What minimum rights do you need at the MDS? A Provider Superuser B Customer Manager C Customer Superuser D Global Manager Answer: D QUESTION: 172 One of your customers will not renew their subscription for the IPS Software Blade, and decides to cancel their subscription early What happens if they don't allow the IPS service to expire? A When the subscription has ended, the IPS falls back to run only checks that were active with the first version published B Since the customer is still subscribed to IPS service via MDG, all things run as before The MSP has to take care that customers will renew their subscription C New updates are not possible after the IPS service blade has ended, but all checks being downloaded before are still configured and active D IPS update service is free of charge and therefore there is no time limit for it Answer: A QUESTION: 173 You manage several customers with Multi-Domain Management with Provider-1 Two of the customers need to be connected via a global VPN using VPN Communities in a Global Rule In the MDG, you configure both Gateways to be enabled for Global use Then you define a Global VPN Community in the Global SmartDashboard How do you configure a rule so that encrypted HTTP traffic is accepted between the corresponding Gateways? A In the menu of the Global SmartDashboard, select Policy > Convert To Simplified Mode, follow the Wizard and define a rule accepting HTTP traffic that fits to the community listed in the column VPN B It's possible to define Global VPN Communities, but it is not possible to use them in a Global Rule Base C In the Global SmartDashboard, define a rule accepting the wanted traffic In the column VPN select the VPN community y5o8u have defined D After having defined a Global VPN Community, the Global Rule Base needs to be assigned to both customers The VPN can only be defined in each (local) CMA individually Answer: A QUESTION: 174 Steve is the Multi-Domain Management with Provider-1 Superuser of an MSP having a Provider-1 R71 environment with 2 MDS Manager systems, 4 MDS Containers and 2 MLM's One of the customers of the MSP requires redundancy for the CMA's Steve has already added a secondary CMA, but the customer insists on having one more CMA What is the best way to do this? A Steve can add a third CMA on the same MDS as the secondary CMA as a single customer can only use up to two MDS Containers for CMA's B Provider-1 only supports 2 CMA's per customer, so Steve will have to install a Security Management Server for backing up the CMA C This is not possible as Provider-1 supports only one backup / secondary CMA D Steve can add a third CMA on another MDS Container Answer: D QUESTION: 175 Select the correct statement about the following Multi-Domain Management with Provider-1environment example A This will never work because all the MDS containers must be on the same LAN and it is also a license violation B This setup will not work as the MDS Co5n9tainer-HA can only host CMA-HA's C This will not work as the number of CMA-HA's must be equal to the number of primary CMA's D This setup will work without any issues as Provider-1 supports a mix of Primary and Secondary CMA's on the same MDS Container as long as they are of different customers Answer: D QUESTION: 176 In Multi-Domain Management with Provider-1 R71, the Security Management backup server can be installed on: A any platform where Security Management Server is supported B any platform where Security Management Server is supported except Windows or Nokia IPSO C SecurePlatform or Windows Server D only SecurePlatform Pro Answer: B QUESTION: 177 As in the example below, MDS-ManagerAndContainer is Active whereas MDS-Manager2 is in Standby mode If a Multi-Domain Management with Provider-1 Superuser logs into MDS- ManagerAndContainer in Read/Write mode using the MDG while the first user is still logged in, and another Provider-1 Superuser tries to log in to MDS-Manager2, what will happen? The second user will: A get an application error and the MDG will close B get a message informing him that another user is logged in with Read/Write access Hence, he will be allowed to log in with Read-Only access C also be allowed to log in through the MDG in Read/Write mode and they can both make changes to the Provider-1 configuration within the MDG D get a message informing him that another user is logged in with Read/Write access, and an option to disconnect the first user will be given QUESTION: 178 Which of the following is the correct syntax for mirroring all CMA's from FirstMDS to SecondMDS? A cma_mirror_all -s FirstMDS -t SecondMDS B p1shell/mirrorcma -s FirstMDS -t SecondMDS -c 2 C mdscmd mirrorcma -s FirstMDS -t SecondMDS -c 2 D mirrorcma -s FirstMDS -t SecondMDS -c 2 Answer: C QUESTION: 179 Let's assume that your Multi-Domain Management with Provider-1 configuration has only one MDS You want the installation to be redundant, so you decide to set up a secondary MDS Container and Manager While completing the installation, you need to provide the activation key The installation is completed after a reboot The final steps are taken with the MDG connecting to the primary MDS Which of the following statements is TRUE? A When the activation key is provided, synchronization at MDS as well as CMA level is started automatically B The first step is to define the secondary MDS in the MDG and to provide the activation key After this is done, it is not possible to synchronize at MDS level only because only the complete configuration of a MDS can be synchronized (including all CMAs) C Before synchronization can start, both the activation key and performing an Install Database are necessary D When the secondary MDS is defined in the MDG and the activation key has been correct, synchronization at the MDS level can be started immediately Answer: D QUESTION: 180 NetSec MSP has Multi-Domain Management with Provider-1 R71 in their New York network They have 1 MDS Manager and 1 MDS Container on a Solaris server with 10 CMA's NetSec has recently setup a network in Dallas and wants to use the Provider-1 MDS Container hosting backup CMA's for all the 10 customers The management is not in favor of buying a Solaris Server, hence they are asking if they can use SecurePlatform on Intel hardware How can NetSec implement this requirement? SecurePlatform in Dallas and then associate the two to enable High Availability' B As it is not possible to have a secondary CMA on a different operating system, NetSec will have to install 10 Security Management Servers to backup the CMA's' C They can have the new Provider-1 R71 MDS Container on SecurePlatform and host all the secondary CMA's on this MDS; Provider-1 R71 HA supports different operating systems' D They will have to buy a Solaris Server to install the MDS Container and host the secondary CMA's on that as it is required for the HA systems to be running the same operating system and version' Answer: C QUESTION: 181 When importing the configuration of a Management Server, the CMA is also imported The name of the CMA is the same name that the Management Server had before How do you configure a name change to the CMA before the CA is re- established again? A At the MDS, change to the corresponding CMA context using the mdsenv command Then issue the command fwm sic_reset to reset the CA completely B In the MDG, select the CMA you want to change With a right-click on the object, select edit and change the name in the window that opens C In the CLI of the MDS environment, issue the command fwm sic_reset You will be asked which SIC you want to reset Select the appropriate CMA and the name as well as the CMA will be changed D The name of a CMA cannot be changed by design because this name is used in certificates Answer: A QUESTION: 182 Importing an existing Management Server configuration into a MDS via CLI might be useful First, the new customer needs to be defined After having defined the CMA, an existing configuration can be imported How can this be done? A At the CLI of the MDS type\linecma_migrate B It is not possible to import a configuration using CLI This can only done using the MDG C At the CLI of the MDS type\linecma_migrate –s -t D At the CLI of the MDS type\linecma_migrate -t –s Answer: A CheckPoint 156-815-71 Exam (Check Point Certified Managed(R) Security Expert R71) Detailed Information Training & Certification Check Point offers a wide range of education programs, professional certifications and self-study resources developed in-house by Check Point security experts. Training is available from our global network of Authorized Training Centers (ATC). TRAINING CALENDAR FIND A TRAINING CENTER CERTIFICATION FAQ Training Together with our Authorized Training Centers, we offer comprehensive technical training and certifications for IT security professionals who deploy and manage Check Point Security solutions. Entry-level Security Awareness Text book and course covers important principles of CyberSecurity from a vendor neutral perspective. Concepts include issues of physical and document security along with data protection and recovery in the event of data or systems loss. Security Principles Associate Core Security Administrator Training Three-day course covers everything you need to start-up, configure and manage daily operations of Check Point Security Gateway and Management Software Blades systems on the GAiA operating system. Security Administrator R77.30 Security Administrator R80 Core Security Expert Training Advanced three-day course teaches how to build, modify, deploy and troubleshoot Check Point Security Systems on the GAiA operating system. Hands-on lab exercises teach how to debug firewall processes, optimize VPN performance and upgrade Management Servers. Security Engineering NextGen Security Training Learn how to deploy the latest cyber-security solutions to defend and prevent today’s evolving threats Threat Prevention Secure Web Gateway Advanced Security Training Learn to manage virtualized security in high-end networks and advanced security optimization techniques. MDSM with VSX Security Master Custom Training Certifications Check Point Certifications mean expertise with the technology that secures the internet for all Fortune and Global 100 companies. The benefits of becoming Check Point certified include the skills to support and sell Check Point products, 2-year expert access to our SecureKnowledge database and advanced product documentation. Getting Started: A Check Point UserCenter or PartnerMap account is required to receive certification benefits. You can create a new account at the User Center. If you are not sure about your account, please contact Account Services for verification. You also need a Pearson VUE account, and the email address should be the same as your UserCenter account. Check Point Certified Security Administrator (CCSA) R80 Essential certification for IT Admins who manage daily operations of Check Point Security solutions. Course Description and Exam Information Check Point Certified Security Administrator (CCSA) R77.30 Essential certification for IT Admins who manage daily operations of Check Point Security solutions. Course Description and Exam Information Check Point Certified Security Expert (CCSE) R77.30 The next level of certification proves troubleshooting skills and the ability to maximize the performance of security networks. Course Description and Exam Information Check Point Managed Security Expert (CCMSE) Advanced certification proves expertise in Multi-Domain Security Management with Virtual System Extension. Course Description and Exam Information Check Point Certified Security Master (CCSM) R77.30 Our most technical certification proves advanced use of time-saving commands to configure and troubleshoot Check Point Security Systems. GENERAL INQUIRIES Q: What is the difference between “Certification” and “Accreditation”? A: Check Point recognizes those professionals who have passed a rigorous, thorough examination process with a “Certification”. Certifications are based on proctored exams derived from comprehensive job models and detailed instructional objectives. Accreditations are derived from product specific content exams delivered in a less formal examination setting and recognize an individual’s effort to stay current on the latest products. Q: What versions are available? A: Our Current certifications are based on R77.30 and the new R80. Q: How long will R77.30 be available? A: Current projections have the R77.30 exams retiring 3rd quarter 2017. Q: How long does a certification last? A: Certification, like security, must be kept current to be truly effective - which is why we strongly encourage you to constantly refresh and keep your certification current. Certifications expire after 24 months. Q: Where can I take a Check Point certification exam? A: Check Point professional certification exams are proctored through Pearson VUE, a third party testing vendor with over 3.500 locations worldwide. You can register for any Check Point exam and earn your certification by visiting Pearson VUE website and creating a Web Profile. Q: Do I have to take classes in order to take the exams? A: No, it is possible to take an exam with only your own experience or self-study using the Check Point courseware, but we highly recommend taking a class instead. Instructor-led training accelerates and focuses your learning, gives you hands-on experience and an opportunity to make mistakes in the lab, and is much more cost-effective than self-study in your spare time. CHECK POINT EDUCATION SERVICES CERTIFICATION FAQ Updated September 2016 2 Q: What certifications are available? A: Check Point certifications are structured around comprehensive job models for administration, engineering (Expert), enterprise management, and advanced systems (Security Master). Certifications include: Core Security courses establish a strong foundation in essential Check Point product knowledge and skills Certifications Related Courses Exams CCSPA Check Point Certified Security Principles Associate Principles of Network Security #156-110 CCSA Check Point Certified Security Administrator Check Point Security Administration #156-215 CCSE Check Point Certified Security Expert Check Point Security Administration #156-215 Check Point Security Engineering #156-315 Advanced Specializations recognize your proficiency and expertise in specific disciplines and technologies Certifications Related Courses Exams CCSM Check Point Certified Security Master Check Point Certified Security Master #156-115 CCMSE Check Point Managed Security Expert Multi-Domain Security Management with Virtual System Extension #156-820 Q: What are the prerequisites for each Check Point certification? A: Check Point certifications are designed to build upon the knowledge and skills of the previous courses, reinforcing lessons learned and extending your competencies with ever more complex and valuable skills. Certifications Prerequisites CCSPA Check Point Certified Security Principles Associate None CCSA R77 Check Point Certified Security Administrator R77 TCP/IP and routing fundamentals CCSA R80 Check Point Certified Security Administrator R80 TCP/IP and routing fundamentals CCSE R77 Check Point Certified Security Expert R77 CCSA R77 CCSE R77 Update Check Point Certified Security Expert R77 Any prior CCSE up to R65 CCSM Check Point Certified Security Master R77 CCSE R77 CCMSE R77 Check Point Managed Security Expert R77 CCSE R77 Updated September 2016 3 Q: What courses should I take to prepare for the exams? A: To help prepare for exams, you should consider the following corresponding courses: Core Security courses establish a strong foundation in essential Check Point product knowledge and skills Exams Courses Certifications #156-110 Principles of Network Security CCSPA Check Point Certified Security Principles Associate #156-215 Check Point Security Administration R80 CCSA R80 Check Point Certified Security Administrator R80 #156-215 Check Point Security Administration R77 CCSA R77 Check Point Certified Security Administrator R77 #156-215 Check Point Security Administration R77 CCSE R77 Check Point Certified Security Expert R77 #156-315 Check Point Security Engineering R77 #156-915 CCSE R77 Update CCSE R77 Update Check Point Certified Security Expert R77 Advanced Specializations recognize your proficiency and expertise in specific disciplines and technologies Exams Courses Certifications #156-115.77 Check Point Security Master R77 CCSM R77 Check Point Certified Security Master #156-820.77 Multi-Domain Security Management with Virtual System Extension CCMSE R77 Check Point Managed Security Expert R77 Q: Is study material available? A: Exam objectives are posted on the Education Services page for reference, but all official training materials are provided when you attend instructor-led training through one of our Authorized Training Center (ATC) partners. Q: Where can I find training classes? A: Courses are offered through our network of over 230 Authorized Training Centers (ATC) around the globe. Use our partner locator to find an ATC near you and sign up for training today! Q: Are classes available globally? A: Yes! We have Authorized Training Centers (ATC) in over 42 countries worldwide - just use our partner locator to find an ATC near you and sign up for training. If for any reason you can't find an ATC near you, send an email to us directly at training@checkpoint.com and ask about on-site training options. Q: How long are the classes recommended for certification exams? A: Check Point recommends minimum time frames for each course, but individual Authorized Training Centers (ATC) may choose to adjust the time to offer more 'intensive' courses or to cover topics in more detail. You should check with your local ATC for the exact length of each course to be sure the time fits your schedule. Updated September 2016 4 Q: I know that CCSA certification is a prerequisite for CCSE. Can I achieve a CCSE R80 certification with a CCSA R70 or later certification? A: No. Since R80 is a completely new product version with many new features, only CCSA R80 certification provides the background necessary to be a prerequisite to CCSE R80 certification. However, if you have a CCSE based on NGX or the Blade technology, you are eligible to take our upgrade exam #156-915 to earn your CCSE R80 certification. Q: When will my R77 certifications expire? A: Check Point Certifications are good for 24 months. Q: My R70 certifications have already expired. Do I need to start over with CCSA R80 to update to CCSE R80? A: Actually, you don’t. Even though your certification has expired, the eligibility for updates to the latest version has not. If you ever held a CCSE certification, you are eligible for the Update exam. Q: Why has the 156-915.77 exam been removed from the exam list? A: The 156-915.77 exam was retired as soon as the 156-915.80 exam was released. Check Point only offers updates to the latest version of the product. Q: How can I learn about updates in the Check Point Certified Professional Program? A: You can always find the latest information on our News and Updates page, including special offers on the most indemand courses and certifications. Back to top MY INFORMATION Q: Why is my Check Point Professional ID Number important? A: It represents your personal identification with Check Point Software Technologies and establishes proof of your certification. You are only allowed one Certified Professional ID number. Q: How do I get my Check Point Professional ID Number? A: It is assigned to you when you register with VUE for the first time to take an exam. It will be in the form CP00000nnnnn. Q: When do I use my Check Point Professional ID Number? A: Whenever you contact VUE to register for another exam session, and whenever you contact Check Point regarding any certification issue. Q: Why do I need to provide an email address? A: An email address is necessary in order to create your User Center account - your access point for certification benefits - as well as keep you up to date with any important changes or updates. Q: If I change jobs, will I still have access to my certification information and benefits? A: Yes! Your certification is yours. However, since your email address is based on your work email you will want to contact Account Services via accountservices@checkpoint.com to update your User Center account and request that your information be linked to your new email address. Q: How do I advise Check Point of any change of address or other relevant information? A: You can send your profile updates to accountservices@checkpoint.com. Back to top Updated September 2016 5 WHAT ABOUT THE BENEFITS Q: I just passed my exams. When can I expect to receive my certificate? A: Check Point now provides e-Certificates that you can access from your User Center profile. Once we receive your exam results we'll update your User Center account with your new credentials, giving you immediate access to your online benefits like Access to SecureKnowledge and your on-line Certification Profile. Q. How do I download the electronic copy of my certification? A: To download your certificate(s), please follow the instructions below. 1. Log into User Center at https://usercenter.checkpoint.com/usercenter/portal 2. Click "Assets/Info". 3. Click "My Certifications" under "My Info" option. 4. Click "Download" to the right of the certificate to open/save/print. a. Open to print. b. Save to print later. c. Cancel to do nothing. Q: What type of SecureKnowledge access do CCSA's get? A: Advanced Access for the duration of the CCSA contract. Q: What SecureKnowledge access does a CCSE get? A: Advanced Access for the duration of the CCSE contract. Q: What SecureKnowledge access does a CCSM get? A: Expert Access for the duration of the CCSM contract. Q: What SecureKnowledge access does a CCMSE get? A: Advanced Access for the duration of the CCMSE contract. Q: How do I access my benefits? A: By setting up a User Centre account based on the email address you used with VUE, you can have access to our Certified Professionals Only web site and to advanced features of Secure Knowledge. Please try the following: If you do not currently have a User Center account, please visit the following URL: https://usercenter.checkpoint.com/usercenter/index.jsp You may reference at the bottom of the page a section titled "New Customers": 1. Click on the hyperlink titled "Sign Up Now!" 2. Begin completing your profile. 3. Use the email ID provided VUE for testing. 4. Set your own password. Q: How do I find the Certified Professionals Only website? A: By clicking on the link https://www.checkpoint.com/services/education/cpo/index.html Q: Do I have access to Check Point online technical support? A: Yes. As a Certified Professional you have Advanced Access to SecureKnowledge, our online technical knowledge database with thousands of solutions, how to articles, and troubleshooting tips to solve your most difficult issues. Q: Are there logos associated with Check Point certifications? A: Yes. As a certified professional you have usage rights to the logo for your certification level. Logos for each Check Point certification are downloadable from the Certified Professional Only website. Updated September 2016 6 Q: Will becoming a Check Point Certified Professional improve my career or employment opportunities? A: Companies hire certified professionals to ensure maximum security and availability of valuable business assets, and know certified professionals are more efficient, productive, and deliver lower total cost of ownership from Check Point solutions. And as one of over 50,000 Check Point Certified Professionals worldwide, you'll get immediate recognition of your experience, knowledge, and abilities while investing in your professional development and security career. Q: Where do I go to access my benefits? A: All benefits are accessed through your User Center account. Create a User Center account now if you don't already have one. If you have any problems with creating your account and linking your certifications, contact accountservices@checkpoint.com Q: Why is my certification information not listed in my User Center account? A: Your certification information could not be listed in your User Center account for one of the following reasons: • We tried to activate your benefits but there was no User Center account with the email address we have on file for you. Please check to ensure that the email account you provided VUE for registration matches the email account you used to set up your User Center account. • The benefits you received from a certain Check Point certification have expired. • We might not have received your results from Pearson VUE. If you do not see your benefits or certification listed with your User Center account, send an email to accountservices@checkpoint.com and we'll try to resolve the issue for you. Q: What email address should be used when registering for an exam? A: It is important that the email address used when registering for an exam is the email address associated to your User Center profile. This ensures that all certifications are reflected within the User Center and the e-certificate can be downloaded via the account. Q: Can certifications get tied to an alias email address? A: All certifications must be tied to a person-specific email address. Q: How do I update the email address associated to my User Center profile? A: For assistance or the steps of how to update your email address online, please contact our Account Services department for assistance; accountservices@checkpoint.com. Q: What should I do if my Pearson VUE profile has the wrong email address? A: Please contact Pearson VUE for assistance; http://www.pearsonvue.com/checkpoint/contact/ Back to top TELL ME ABOUT THE EXAMS Q: What is the difference between “low stakes” and “high stakes” exams? A: All Check Point exams are delivered through Pearson VUE. “Low stakes” exams are those delivered over the Internet to your desktop. They do not require attendance at a Pearson VUE Authorized Testing Center (ATC). “High stakes” exams are only delivered at Pearson VUE Authorized Testing Centers (ATC) and delivery meets certain exacting compliance standards. Q: In what order should I take the exams? A: Courses, certifications, and exams are all designed to build on the lessons learned and develop your skills and knowledge, so we recommend starting with CCSA R77 and CCSE R77 to get a core security foundation. From there you can choose the specialization or area of expertise that best matches your job role or career goals. See the complete list of courses, exams, and prerequisites earlier in the FAQ for more information. Updated September 2016 7 Q: How much do the exams cost? A: Exams vary in price between US $150-$200, but exact pricing is available through Pearson VUE. Q: Where can I take a Check Point certification exam? A: Check Point exams are offered through Pearson VUE, a third party testing vendor with over 3,500 testing centers worldwide. Register for your exam at a testing location near you. Q: What is the format of the exams? A: The exams are composed of multiple choice and scenario questions. All questions are “Select the BEST answer” type questions. There are no multiple response. Q: How long are the exams? A: We use a 90-minute exam in all English-speaking countries. Non-English speaking countries receive an additional 30 minutes. Q: How do I know I am ready for an exam? A: If you are preparing for the CCSA certification and want to take the 156-215 exam, you can determine if you are ready by taking the 156-601 CCSA R77 practice exam. This exam presents 40 questions from a subset of the actual exam pool. Feedback is limited to providing the correct answer during the exam. If you are preparing to complete the CCSE certification and want to take the 156-315 exam, you can determine if you are ready by taking the 156-602 CCSE R77 practice exam. This exam presents 40 questions from a subset of the actual exam pool. Feedback is limited to providing the correct answer during the exam. Q: Are the Check Point certification exams adaptive? A: Check Point has no plans at this time to move into adaptive exams. Q: Do any of the exams contain questions where the correct answer relies on the selection of multiple responses, even though the exam doesn't indicate to check more than one? A: Although the instructions for each exam state that there is one BEST answer, in truth the best answer may be a combination of more than one in the final results. We do this to evaluate how each student reaches their conclusion and makes difficult choices, just like you will be faced with on the job. However, there is no partial credit for incorrectly marked questions. Q: Should I have experience with Check Point products before attempting to pass an exam? A: Surveys of certified professionals suggest that a candidate have one to two years’ experience with the product in a production environment before attempting the CCSA certification. Since that isn’t practical in today’s environment, we recommend six months after training. A similar interval trended when studying the Engineering tasks of a certified CCSE professional. We recommend one year. The new Check Point Security Master certification job profile suggests five years’ experience before challenging the exam. Of course, this varies by individual. Q: Can I take the CCSA and CCSE exams on the same day? A: Yes, you can take the CCSA exam and later that same day, challenge the CCSE exam. Q: Does Check Point have an exam retake policy? A: Yes. If you fail an exam and want to retake it, the following applies: • Wait 24 hours after first unsuccessful attempt • Wait 30 days after each subsequent attempt thereafter Note: Once you pass an exam you cannot take it again. Updated September 2016 8 Q: I have taken the exam twice, and scored exactly the same thing. How is this possible? Is there a problem with the exam or the testing software? A: This is actually quite common, and indicates how reliable Check Point's exams are in testing your knowledge and skills. To create the best certification exams, we focus on consistency and on how an exam will measure competencies. There is a related learning/testing condition called "plateauing". Let's say you've studied hard, practiced the labs and exercises, and absorbed all you can through the current study approach. Studies and experience show you will consistently score the same regardless how much you review the material beyond that point. In this case the best solution for you would be to take a different study approach to gain new insight, and retain more knowledge than you would in just one method - we suggest taking an additional class, or working through some different practice exercises. Q: Does Check Point penalize incorrect answers? A: Check Point does not subtract points from your score for answering a question incorrectly. You will simply not get credit for that question. When taking one of our exams, answer as many questions as you can, even if you are not certain of your answer. Back to top MAINTAINING CURRENCY Q: I wanted to extend my certification by retaking my last exam but got the information from Pearson VUE that I’m not allowed to do so because I’ve already finished that. How do I extend my certification? A: Check Point policy is that you do not retake an exam you have already passed. You either update or upgrade. Ideally, the best course is to take the next higher exam. Q: What is the difference between “Inactive” and “Valid”? A: “Inactive” means that a candidate has not kept their certifications current in an aggressive threat environment. All professional certifications - those taken in a proctored exam environment - are good for, or considered “Current”, for two years. “Valid” refers to the candidate actually having met the requirements for Certification. Q: What are Continuing Education Credits? A: Check Point values lifelong learning. It is essential in an ever changing threat environment. Candidates can acquire Continuing Education Credits by participating in certain events, or by taking certain Low Stakes exams. Candidates are eligible to acquire two Continuing Education credits in a two year certification period Q: What low stakes exams are eligible for Continuing Education Credits? A: Where Check Points High stakes professional exams are primarily focused on performance-based questions, lowstakes exams are focused more on product knowledge and product features. Currently, on the Pearson VUE exam site, the following low stakes exams are available: 156-728 – Gaia Overview 156-729 – Advanced IPS 156-730 – SandBlast 156-733 – Mobile Threat Prevention SE Any two of these will renew your current CCSE certification for one year 1. What are the pre-requisites for the CCSE R75 exam? CCSA R70 or CCSA 71 or CCSA R75. 2. How can I update my R65 certification? If you have any CCSA R60 certification, take the CCSA R70/71 Update Training Blade to update your CCSA certification. If you have a CCSE R60 certification, take the CCSE R70/71 Update Training Blade to update your CCSE certification. 3. How long is my certification valid? Check Point certifications are valid for 2 years. CCMAs are valid for 3 years. Any certification more than three (3) years old is not considered current. Certifications become inactive after five years. Your benefits may be suspended if your certification is not current. Your certification can be maintained with annual continuing education credits. 4. What are ‘continuing education credits’? Continuing education credits help you maintain Check Point certifications without starting over with every product release. Continuing education credits can be earned in a variety of ways like completing shorter training lessons (Training Blades), by participating in our test development process, and even attending CPX. 5. What are the pre-requisites for CCMA? CCSE is mandatory; CCMSE is suggested. 6. Do you have a test-out option? Though highly recommended, it is not a requirement to attend a training course before challenging the exam. You may test at any time, however it is advised you spend at least 6 months working with Check Point products before attempting to achieve certification. 7. Are study materials available? Free study guides and practice exams are available for download at http://www.checkpoint.com/services/education/index.html#resources. Courseware can be purchased on our eStore and Training is available from an ATC. 8. How soon can I re-take an exam if I fail? If you fail an exam you must wait 24 hours before your 2nd attempt, and 30 days for the 3rd attempt. Once you pass a test you cannot take it again for a higher score. 9. Can I get exam insurance? Students automatically get a 50% re-take discount on any 2nd attempt of the CCSA and CCSE R75 exams. 10. I only failed by 1 point and based on my calculations I should have passed – what happened? The function of certification is to provide proof the Check Point Certified professional is qualified to protect the lifeblood of organizations – their data. Check Point takes this very seriously and we constantly strive to administer the most effective exams. Passing is calculated by comparing the number of questions answered correctly versus the number of questions answered incorrectly. Not all sections of the test are weighted equally. ©2012 Check Point Software Technologies Ltd. . Classification: [Unrestricted] — For everyone | P. 2 11. Can I take any R65 level exams? No, all R65 exams have been retired except for the Japanese versions. Our philosophy is to provide training and certification only for current technologies so our partners and customers will always benefit from the latest security advancements. 12. Where can I find more information about Check Point Certified Professionals? The Check Point Certified Professionals website and newsletter are a benefit which contain special information and resources that are not available to the public. 13. What happens when I pass my exam? When will I receive my Certificate? After you pass a Check Point exam at VUE, your exam results are uploaded. On the 15th and 30th, we process all certification results and order certification kits. It takes 6-8 weeks to receive your certificate. Your advanced access to Secure Knowledge and the Certified Professionals website is established once you achieve certification. 14. Why can’t I have more than one account at Pearson VUE test centers? Check Point only allows one Pearson VUE account to track your Check Point exams. If you change companies, please update the contact information in your Pearson VUE account instead of creating a new one so your Check Point certifications will follow you. You can verify your accounts with Customer Service here http://www.vue.com/checkpoint/contact/ 15. What happens if someone gets caught cheating? How do you prevent it? Every individual who takes an exam signs our Non-disclosure agreement. Anyone caught in the act of cheating or sharing exam items will have their Check Point certifications revoked for 2 years. All testing privileges and partner program participation will be deactivated during this time. Check Point collaborates with major technology companies to prevent cheating through test pattern analysis and distribution best practices. Together we identify and take legal action against unauthorized test centers and inaccurate “brain dump” sites. 16. What are the benefits of Check Point certification? Check Point Certified Professionals receive access to the Advanced SecureKnowledge base, Certified Professionals only website and quarterly newsletter for 2 years. Check Point Certified Master Architects (CCMA) receive 3 years Expert level access to SecureKnowledge. 17. How do I access my certification benefits? Make sure your Check Point User Center (UC) email address matches the email address registered with Pearson VUE. Your UC profile will automatically be updated with each certification, including advanced access to SecureKnowledge and the Certified Professionals only website. Check Point Certified Security Administrator (CCSA) R80 Today, managing security is a complex endeavor. The key to managing this complexity is through security consolidation – bringing all security protections and functions under one umbrella. With R80 management, security consolidation is fully realized. This three-day course covers everything you need to start-up, configure and manage the daily operations of your Check Point infrastructure with R80. TRAINING CALENDAR SCHEDULE YOUR EXAM SEARCH FOR YOUR LOCAL ATC Course Description Learn How To Install R80 management and a security gateway in a distributed environment Configure objects, rules, and settings to define a security policy Work with multiple concurrent administrators and define permission profiles Configure a Virtual Private Network and work with Check Point clustering Perform periodic administrator tasks as specified in administrator job descriptions Prerequisites Basic knowledge of networking 6 months to 1 year of experience with Check Point products recommended How You Will Benefit Be prepared to defend against network threats Evaluate existing security policies and optimize the rule base Manage user access to corporate LANs Monitor suspicious network activities and analyze attacks Troubleshoot network connections Implement Check Point backup techniques Exam Information Exam# 156-215.80 What You Need To Know Check Point Technology Overview Security Policy Management Monitoring Traffic and Connections Network Address Translations Basic Concepts of VPN Managing User Access Working with ClusterXL Administrator Task Implementation Prerequisites 6 months to 1 year of experience with Check Point products recommended Check Point User Center account Pearson VUE Test Center account How You Will Benefit CCSA’s rank higher than other security vendor professionals Validation you have the skills to implement the latest network security advancements Certified Professionals community, newsletter and special web access Check Point Certified Security Administrator (CCSA) R77.30 Advance your knowledge on the GAiA operating system! 3-day course covers everything you need to start-up, configure and manage daily operations of Check Point Security Gateway and Management Software Blades systems on the GAiA operating system. TRAINING CALENDAR SCHEDULE YOUR EXAM SEARCH FOR YOUR LOCAL ATC DOWNLOAD STUDY GUIDE Course Description Learn How To Install the security gateway in a distributed environment Configure rules on Web and Gateway servers Create a basic rule base in SmartDashboard and assign permissions Schedule backups and seamless upgrades with minimal downtime Monitor and troubleshoot IPS and common network traffic Prerequisites Basic knowledge of networking Windows Server and/or UNIX skills Internet and TCP/IP experience How You Will Benefit Be prepared to defend against network threats Evaluate existing security policies and optimize the rule base Manage user access to corporate LANs Monitor suspicious network activities and analyze attacks Troubleshoot network connections Protect email and messaging content Exam Information Exam# 156-215.77 What You Need To Know Check Point Technology Overview Deployment Platforms and Security Policies Monitoring Traffic and Connections Network Address Translations User Management and Authentication Using SmartUpdate Implementing Identity Awareness Configuring VPN tunnels Resolving security administration issues Prerequisites 6 months to 1 year of experience with Check Point products recommended Check Point User Center account VUE Test Center account How You Will Benefit CCSA’s rank higher than other security vendor professionals Validation you have the skills to implement the latest network security advancements Certified Professionals community, newsletter and special web access Security Engineering (Check Point Certified Security Expert (CCSE) R77.30) Advanced 3-day course teaches how to build, modify, deploy and troubleshoot Check Point Security Systems on the GAiA operating system. Hands-on lab exercises teach how to debug firewall processes, optimize VPN performance and upgrade Management Servers. See course description TRAINING CALENDAR SCHEDULE YOUR EXAM SEARCH FOR YOUR LOCAL ATC DOWNLOAD STUDY GUIDE Course Description Learn How To Backup your Security Gateway and Management Server Build, test and troubleshoot a clustered Security Gateway Upgrade and troubleshoot a Management Server Configure and maintain security acceletration solutions Manage, test and optimize corporate VPN tunnels Prerequisites Security Administration Course or CCSA certification (R70 or later) Windows Server, UNIX and networking skills and TCP/IP experience Certificate management and system adminstration How You Will Benefit Build, test and troublehoot numerous deployment scenarios Apply insider tips troubleshooting Check Point Security Systems Practice advanced upgrading techniques Migrate to a clustering security solution Create events for compliance reporting Manage internal and external access to corporate resources Exam Information EXAM #156-315.77 What You Need To Know Check Point Technology Overview Deployment Platforms and Security Policies Monitoring Traffic and Connections Network Address Translations User Management and Authentication Using SmartUpdate Implementing Identity Awareness Configuring VPN tunnels Resolving security administration issues Prerequisites CCSA Certification – R70 or later Check Point User Center account VUE Test Center account Get Ready Download the study guide Search for training from your local ATC Schedule your exam at VUE test centers Update Exam UPDATE EXAM #156-915.77 What You Need To Know If you have any CCSE certification, you can save time and maintain your certification with the CCSE Update exam! The CCSE Update only tests your knowledge on the latest product release. To prepare you should train or study the full CCSE course. Prerequisites CCSE Certification – any previous version Check Point User Center account VUE Test Center account MDSM with VSX (Multi-Domain Security Management with Virtual System Extension) 5-day advanced course teaches how to design, install, configure and manage Multi-Domain Security Management with Virtual System Extension. TRAINING CALENDAR SCHEDULE YOUR EXAM SEARCH FOR YOUR LOCAL ATC Course Description Learn How To Install, configure and troubleshoot Multi-Domain Security Managment Configure and implement a Global Policy Transition and consolidate physcial firewalls to a virtualized environment Prerequisites CCSE or equivalent experience Check Point User Center account VUE Test Center account How You Will Benefit Consolidate multiple firewalls onto a single management platform Convert a security management server to a domain management server Use advanced migration tools to quickly migrate existing configurations Apply common troubleshooting best practices Implement MDS High-Availaibility Exam Information Exam #156-820.77 What You Need To Know Install, configure and manage the MDM environment Discribe common deployment scenarios Describe the traffic inspection process Configure DMS High Availability Configure and implement a Global Policy Apply common troubleshooting practices Prerequisites CCSE R75 or later 6 months to 1 year of experience with Check Point products Check Point User Center account How You Will Benefit Check Point Certified Professionals rank higher than other security vendor professionals Validation you have the skills to manage enterprise security deployments Certified Professionals community, newsletter and special web access Check Point Certified Security Master (CCSM) R77.30 Our most advanced technical 3-day course teaches how to use advanced commands to configure and troubleshoot Check Point Security Systems. 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